Characterization of a novel galactose β1,3-N-acetylglucosaminyltransferase (β3Gn-T8): the complex formation of β3Gn-T2 and β3Gn-T8 enhances enzymatic activity
نویسندگان
چکیده
منابع مشابه
Down-regulation of β-1,3-N-acetylglucosaminyltransferase-8 by siRNA inhibits the growth of human gastric cancer.
β-1,3-N-acetylglucosaminyltransferase-8 (β3Gn-T8) is the most recently identified enzyme in the β3Gn-T family, but its biological function is poorly understood. To elucidate the effects of β3Gn-T8 on gastric cancer behavior, β3Gn-T8 was down-regulated in AGS cells using small interfering RNA (siRNA). The mRNA and protein expression levels of β3Gn-T8 were detected using RT-PCR and Western blotti...
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ژورنال
عنوان ژورنال: Glycobiology
سال: 2005
ISSN: 1460-2423,0959-6658
DOI: 10.1093/glycob/cwi082